In The Unwritten it's pretty clear that Pullman is Cain as well as some other mythological bad guys.The Strange Talent of Luther Strode is about the eponymous character gaining superpowers thanks to the "Hercules Method" based on a Religion of Evil, made by noneless than Cain himself who's alive and is the Big Bad of the story.The Multiversity: In Society of Super-Heroes: Conquerors of the Counter-World #1, Vandal Savage of Earth-40 is heavily implied to be Cain, with the meteor that gave him his powers being the rock that he used to kill Abel.Of course, Vandal never met House of Mystery's Cain before.
Depending on the Writer, Savage can be the real Cain who survived many centuries as well being one of his aliases, all thanks to his immortality.
Plop, a humor/horror comic, has Cain, Abel, and a female character named Eve as the "hosts".Alan Moore used them in his Swamp Thing run, expanding their story and giving them an origin about why they're hosts for the House of Mystery series, being Abel revived in Earth and later his brother Cain to be their hosts.These versions of Cain and Abel were originally created for the horror anthology comic House of Mystery in The '60s as one of the hosts of the magazine until its cancellation, being both brothers living in the aforementored house and who presented the stories to readers.DC Comics has Cain as a character that appeared decades ago and is integral part of the DC Magical/Dark Universe along with his brother Abel, who had less revelevance than his brother.